MHY1485 326914-06-1

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Synonyms

：

Appearance

：

Chemical Formula

：

C17H21N7O4

Solubility

：

Molecular Weight

：

387.39

Storage and Stability

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in stock

CAS No.

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326914-06-1

Purity

：

98%+

Introduction

MHY1485 suppresses the basal autophagic flux. MHY1485 causes the accumulation of LC3II and enlargement of the autophagosomes in a dose- and time- dependent manner.MHY1485 increases phospho-mTOR levels and phosphorylation of downstream S6K1 and rpS6 proteins without affecting total mTOR content, total S6K1 and rpS6 levels. Short-term treatment of ovaries with MHY1485 followed by allo-transplantation promoted secondary follicle growth. Treatment with MHY1485 and subsequent grafting allowed the derivation of mature oocytes and healthy offspring

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MHY1485 326914-06-1

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MHY1485 326914-06-1

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