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Ulixertinib 869886-67-9

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Synonyms
Appearance
Chemical Formula
C21H22Cl2N4O2
Solubility
Molecular Weight
433.33
Storage and Stability
in stock
CAS No.
869886-67-9
Purity
98%+
Introduction
In an A375 melanoma cell line containing a b-RAFV600E mutation, Ulixertinib reduces the levels of phosphorylated ERK2 (pERK) and of the phosphorylation of the downstream kinase RSK (pRSK) with IC50 of 4.1/0.14 μM, respectively. Ulixertinib also inhibits A375 cell proliferation with IC50 of 180 nM. 

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