ZCL278 587841-73-4

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Synonyms

：

Appearance

：

Chemical Formula

：

C21H19BrClN5O4S2

Solubility

：

Molecular Weight

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584.89

Storage and Stability

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in stock

CAS No.

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587841-73-4

Purity

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98%+

Introduction

ZCL278 inhibits Cdc42 GTPase activity by the competition with GTP and inhibits Rac/Cdc42 phosphorylation in a time-dependent manner. ZCL278 (50 μM) inhibits Cdc42-mediated microspike formation and disrupts GM130-docked Golgi structures in serum-starved Swiss 3T3 fibroblasts. In addition, ZCL278 also suppresses Cdc42-mediated neuronal branching and growth cone dynamics as well as actin-based motility and migration in a metastatic prostate cancer PC-3 cell line without cytotoxicity.

Products for scientific research use only

ZCL278 587841-73-4

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ZCL278 587841-73-4

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