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WH-4-023 837422-57-8

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Synonyms ：
Appearance ：
Chemical Formula ：
C32H36N6O4
Solubility ：
Molecular Weight ：
568.67
Storage and Stability ：
in stock
CAS No. ：
837422-57-8
Purity ：
98%+
Introduction
WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.

WH-4-023 shows little activity on p38 and KDR

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