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PD 151746 179461-52-0

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Synonyms ：
Appearance ：
Chemical Formula ：
C11H8FNO2S
Solubility ：
Molecular Weight ：
237.25
Storage and Stability ：
in stock
CAS No. ：
179461-52-0
Purity ：
98%+
Introduction
PD 151746 is a selective, cell-permeable calpain inhibitor with Ki of 0.26 μM for μ-Calpain, about 20-fold selectivity over m-calpain.

In SY5Y cells, PD151746 effectively attenuates the SLLVY-AMC hydrolysis induced by maitotoxin. In HMEC-1 cells, PD 151746 decreases cytotoxicity induced by oxidized low-density lipoprotein (oxLDL). 

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