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IWP-L6 1427782-89-5

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Synonyms
Appearance
Chemical Formula
C25H20N4O2S2
Solubility
Molecular Weight
472.58
Storage and Stability
in stock
CAS No.
1427782-89-5
Purity
98%+
Introduction
IWP-L6 is a highly potent Porcn inhibitor with EC50 of 0.5 nM.

IWP-L6 blocks the phosphorylation of the cytoplasmic Wnt pathway effector Dvl2 in HEK293 cells. In cultured embryonic kidneys, IWP-L6 also inhibits Wnt mediated branching morphogenesis by reversibly blocking Wnt signaling. 

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