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GNE-7915 1351761-44-8

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Synonyms ：
Appearance ：
Chemical Formula ：
C19H21F4N5O3
Solubility ：
Molecular Weight ：
443.40
Storage and Stability ：
in stock
CAS No. ：
1351761-44-8
Purity ：
98%+
Introduction
GNE-7915 is a highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor, with IC50 and Ki of 9 nM and 1 nM, respectively.


GNE-7915 is also a moderately potent 5-HT2B antagonist according to in vitro functional assays. GNE-7915 demonstrates excellent in vitro DMPK with minimal turnover in human hepatocytes. [1]


 
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