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Otenabant CP-945598 686347-12-6

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Synonyms
Appearance
Chemical Formula
C25H25Cl2N7O.HCl
Solubility
Molecular Weight
546.88
Storage and Stability
in stock
CAS No.
686347-12-6
Purity
98%+
Introduction
Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1.

CP-945598 HCl inhibits CB1 receptor with moderate unbound microsomal clearance, low hERG affinity, and adequate CNS penetration. [1] CP-945598 HCl has low affinity with Ki of 7.6 μM for human CB2 receptors.

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