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GNE9605

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Synonyms
GNE-9605
Appearance
Chemical Formula
C17H20ClF4N7O
Solubility
DMSO 89 mg/mL (197.85 mM)
Molecular Weight
449.83
Storage and Stability
10 grams
CAS No.
1536200-31-3
Purity
98%
Introduction
GNE-9605 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 19 nM.IC50 value: Target: LRRK2 GNE-9605 retained excellent predicted human metabolic stability when assayed in human liver microsomes and hepatocytes. In addition, no reversible or time-dependent inhibition of any of the major CYP isoforms was observed.

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