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Cidofovir 113852-37-2

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Synonyms
Appearance
Chemical Formula
C8H14N3O6P
Solubility
Molecular Weight
279.19
Storage and Stability
in stock
CAS No.
113852-37-2
Purity
98%+
Introduction
Cidofovir suppresses virus replication by selective inhibition of viral DNA synthesis.

Cidofovir inhibits human cytomegalovirus (HCMV) infection in cultured cells. Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. Cidofovir also inhibits herpes simplex virus infection. In addition, Cidofovir blocks cell fusion induced by HSV-1 in monkey kidney cells and blocks the expression of HSV-l-specific proteins and the synthesis of viral DNA. 

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