XMD8-87 1234480-46-6

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Synonyms

：

Appearance

：

Chemical Formula

：

C24H27N7O2

Solubility

：

Molecular Weight

：

445.52

Storage and Stability

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in stock

CAS No.

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1234480-46-6

Purity

：

99%+

Introduction

XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations.

XMD8-87 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.

XMD8-87 1234480-46-6

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XMD8-87 1234480-46-6

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CAS No. ：

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