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Apitolisib 1032754-93-0

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Synonyms
Appearance
white powder
Chemical Formula
C23H30N8O3S
Solubility
Molecular Weight
498.6
Storage and Stability
CAS No.
1032754-93-0
Purity
99%+
Introduction
Apitolisib (GDC-0980, RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor withKi of 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Phase 2.

CAS:  1032754-93-0

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