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Neratinib |
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|
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C30H29ClN6O3 |
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DMSO 2 mg/mL (3.59 mM) |
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557.04 |
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20grams |
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698387-09-6 |
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98% |
Introduction
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively.Neratinib (HKI-272) is a tyrosine kinase inhibitor, it is a dual inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.